Canesoral Oral Capsule for Vaginal Thrush

Canesoral Oral Capsule is an effective single dose (one capsule) treatment for vaginal thrush. The Oral treatment offers a discreet and convenient option for people ‘on the go’. It may also be a preferred option when you have your period.

For vaginal thrush in adults, only a single dose (1 capsule) of Canesoral is needed. Canesoral can be taken with or without food.

Do not take Canesoral if you are allergic to medicines containing:

• fluconazole
• other azole antifungals such as miconazole (eg. Daktarin), ketoconazole (eg. Nizoral), clotrimazole (eg. Canesten, Clonea), itraconazole (Sporanox)
• any of the ingredients listed.

Some of the symptoms of an allergic reaction may include skin rash, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath.

Do not take Canesoral if you are taking cisapride (Prepulsid), a medicine used to treat stomach problems. Combining Canesoral with cisapride may cause serious side effects such as an abnormal heart rhythm.

Do not take Canesoral if you are pregnant; suspect you may be pregnant or if you may become pregnant during treatment. Canesoral should not be used during pregnancy as it may affect your developing baby.

Do not take Canesoral if you are breastfeeding. Canesoral passes into breast milk and may affect your baby.

Before you start to take it

Tell your doctor or pharmacist if you are allergic to any other medicines, foods, dyes or preservatives.

Tell your doctor or pharmacist if you have or have had, any medical conditions, especially the following:

• thrush more than twice in the last six months
• liver problems
• kidney problems
• heart problems
• HIV infection or AIDS.
• diabetes

Your doctor or pharmacist may want to take special care if you have any of these conditions.

Tell your doctor or pharmacist before using Canesoral if you are taking warfarin (eg. Marevan, Coumadin), as bleeding or bruising may occur.

Tell your doctor or pharmacist if you are experiencing any of the following:

• Abnormal or irregular vaginal bleeding or blood stained discharge
• Foul smelling or unusual coloured discharge
• Vulval or vaginal sores, ulcers or blisters
• Lower abdominal pain or burning when passing urine
• Fever or chills

If you have not told your doctor or pharmacist about any of the above, tell them before you start taking Canesoral .

Taking other medicines

If you are taking cisapride (Prepulsid), a medicine used to treat stomach problems, do not take Canesoral .

Tell your doctor or pharmacist if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may be affected by Canesoral, or may affect how well it works. These include:

• warfarin (eg. Marevan, Coumadin), a medicine used to prevent blood clots
• phenytoin (Dilantin), a medicine used to treat epilepsy
• cyclosporin (eg. Neoral) or tacrolimus (Prograf), medicines used to prevent organ transplant rejection or to treat certain problems with the immune system
• certain medicines use to treat diabetes such as:
• glibenclamide (eg. Daonil, Glimel), glipizide (Minidiab, Melizide), glimepiride (eg. Amaryl), gliclazide (eg. Diamicron, Glyade)
• pioglitazone (Actos), rosiglitazone (Avandia)
• rifampicin (Rifadin, Rimycin) or rifabutin (Mycobutin), antibiotics used to treat infections
• theophylline (Nuelin), a medicine used to treat asthma
• midazolam (eg. Hypnovel) and triazolam (Halcion), medicines used as sedatives or to treat anxiety
• zidovudine (eg. Retrovir), a medicine used to treat AIDS patients
• hydrochlorothiazide (eg. Dithiazide), a medicine used for treating fluid problems and high blood pressure
• the contraceptive pill (birth control pill).

Talk to your doctor about the need for an additional method of contraception while taking Canesoral . Canesoral may decrease the effectiveness of some birth control pills.

Your doctor can tell you what to do if you are taking any of these medicines.

If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Canesoral.

The active ingredient in Canesoral is fluconazole 150 mg.

Each capsule also contains the following inactive ingredients:

• gelatin
• lactose
• pregelatinised maize starch
• silicon dioxide
• magnesium stearate
• sodium lauryl sulfate
• titanium dioxide (E171)
• TekPrint SW-9008 Black Printing Ink
• TekPrint SW-9009 Black Printing Ink.